bekhterevОбозрение психиатрии и медицинской психологии имени В.М.БехтереваV.M. BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY2313-70532713-055XV. M. BEKHTEREV NATIONAL RESEARCH MEDICAL CENTER FOR PSYCHIATRY AND NEUROLOGY OF THE RUSSIAN FEDERATION MINISTRY OF HEALTH10.31363/2313-7053-2024-902bekhterev-1065Research ArticleНАУЧНЫЕ ОБЗОРЫSCIENTIFIC REVIEWВероятностная диагностика биполярного аффективного расстройства: возможности и ограниченияProbabilistic diagnosis of bipolar affective disorder: possibilities and limitations (literature review)https://orcid.org/0000-0002-9813-3789СимуткинГ. Г.SimutkinG. G.

Симуткин Герман Геннадьевич - д.м.н., ведущий научный сотрудник отделения аффективных состояний

634014 Томск, ул. Алеутская 4

ggsimutkin@gmail.comНаучно-исследовательский институт психического здоровья, Томский национальный исследовательский медицинский центр Российской академии наукРоссияMental Health Research Institute, Tomsk National Research Medical Center, Russian Academy SciencesRussian Federation202415122024584-14560Copyright © Симуткин Г.Г., 20242024Симуткин Г.Г.Simutkin G.G.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.bekhterevreview.com/jour/article/view/1065

В обзоре литературы представлены основные современные данные об эпидемиологии и социально-экономическом значении биполярного аффективного расстройства (БАР), рассмотрены трудности ранней диагностики расстройств биполярного спектра, предикторы биполярного течения аффективных расстройств и вероятностный подход к диагностике БАР, обсуждаются спорные вопросы диагностики смешанных аффективных состояний, применения потенциальных биомаркеров как для диагностики БАР, так и для дифференциальной диагностики униполярной и биполярной депрессии, а также возможные терапевтические подходы при вероятностной диагностике БАР.

The literature review presents the main modern data on the epidemiology and socio-economic significance of bipolar affective disorder (BD), discusses the difficulties of early diagnosis of bipolar spectrum disorders, predictors of the bipolar course of affective disorders and a probabilistic approach to the diagnosis of BD, discusses controversial issues in the diagnosis of mixed affective states, the use of potential biomarkers both for the diagnosis of bipolar disorder and for the differential diagnosis of unipolar and bipolar depression, as well as possible therapeutic approaches for the probabilistic diagnosis of bipolar disorder.

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The authors declare that there are no conflicts of interest present.