bekhterevОбозрение психиатрии и медицинской психологии имени В.М.БехтереваV.M. BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY2313-70532713-055XV. M. BEKHTEREV NATIONAL RESEARCH MEDICAL CENTER FOR PSYCHIATRY AND NEUROLOGY OF THE RUSSIAN FEDERATION MINISTRY OF HEALTH10.31363/2313-7053-2024-1060bekhterev-1071Research ArticleВ ПОМОЩЬ ПРАКТИКУЮЩЕМУ ВРАЧУGUIDELINES FOR THE PRACTITIONERОт патогенеза хронической церебральной ишемии к таргетной терапииFrom the pathogenesis of chronic cerebral ischemia to targeted therapyhttps://orcid.org/0000-0003-2266-9197ЗахаровД. В.ZakharovD. V.

Захаров Денис Валерьевич -доктор медицинских наук, главный научный сотрудник, заведующий отделением интегративной терапии больных психоневрологического профиля

192019, Россия, г. Санкт-Петербург, ул. Бехтерева, 3

St. Petersburg

zaharov_dv@mail.ruhttps://orcid.org/0009-0003-2530-7623ЯрыгинаЮ. В.YaryginaYu. V.

Ярыгина Юлия Владимировна — кандидат медицинских наук, научный сотрудник отделения интегративной терапии больных психоневрологического профиля

192019, Россия, г. Санкт-Петербург, ул. Бехтерева, 3

St. Petersburg

judidu@rambler.ruhttps://orcid.org/0000-0002-7700-2704МихайловВ. А.MikhailovV. A.

Михайлов Владимир Алексеевич - доктор медицинских наук, главный научный сотрудник, научный руководитель отделения интегративной терапии больных психоневрологического профиля и отделения экзогенно-органических расстройств и эпилепсии

192019, Россия, г. Санкт-Петербург, ул. Бехтерева, 3

St. Petersburg

vladmikh@yandex.ruФГБУ «Национальный медицинский исследовательский центр психиатрии и неврологии им. В.М. Бехтерева» Минздрава РоссииРоссияV.M. Bekhterev National MedicalResearchCenterfor Psychiatry and NeurologyRussian Federation202415122024584-1122128Copyright © Захаров Д.В., Ярыгина Ю.В., Михайлов В.А., 20242024Захаров Д.В., Ярыгина Ю.В., Михайлов В.А.Zakharov D.V., Yarygina Y.V., Mikhailov V.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.bekhterevreview.com/jour/article/view/1071

Хроническая прогрессирующая цереброваскулярная патология представляет собой мощный инвалидизирующий фактор современного общества. В основе хронической ишемии головного мозга лежат проблемы микроциркуляции и нейровоспаления, представляющие собой взаимно потенцирующие патогенетические аспекты. В качестве поиска современной патогенетически ориентированной таргетной терапии огромное внимание уделяется церебральной капилляропатии, окислительному стрессу в мозговой ткани и вопросам подавления нейровоспаления. В статье представлены материалы проведенных экспериментальных и клинических исследований экстракта Гинкго билоба и холина, а также их комбинации — Холин Стронг®

Chronic progressive cerebrovascular pathology is a powerful disabling factor in modern society. Chronic cerebral ischemia is based on microcirculation and neuroinflammation problems, which are mutually potentiating pathogenetic aspects. As a search for modern pathogenetically oriented targeted therapy, great attention is paid to cerebral capillary disease, oxidative stress in brain tissue and the issues of suppressing neuroinflammation. The article presents the materials of experimental and clinical studies of Ginkgo biloba extract and choline, as well as their combination — Choline Strong®

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The authors declare that there are no conflicts of interest present.