References

bekhterev

Обозрение психиатрии и медицинской психологии имени В.М.Бехтерева

V.M. BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY

2313-70532713-055X

V. M. BEKHTEREV NATIONAL RESEARCH MEDICAL CENTER FOR PSYCHIATRY AND NEUROLOGY OF THE RUSSIAN FEDERATION MINISTRY OF HEALTH

bekhterev-115

Research Article

В ПОМОЩЬ ПРАКТИКУЮЩЕМУ ВРАЧУ

GUIDELINES FOR THE PRACTITIONER

Когнитивная дисфункция при депрессии у пожилых пациентов с хронической ишемией головного мозга: опыт применения Вортиоксетина (Бринтелликс)

Cognitive dysfunction in elderly patients with depression based on chronic brain ischemia: vortioxetine (Brintellix) experience

Житкова

Юлия Владимировна

Zhitkova

Yu. V.

zhitkova@mail.ru

Хасанова

Дина Рустемовна

Hasanova

D. R.

dhasanova@mail.ru

ГАУЗ «Межрегиональный клинико-диагностический центр»РоссияInterregional Clinical and Diagnostic CenterRussian Federation

ГАУЗ «Межрегиональный клинико-диагностический центр»; ГОУ ВПО «Казанский государственный медицинский университет», РосздраваРоссияInterregional Clinical and Diagnostic Center; Kazan State Medical University, Ministry of Health of RussiaRussian Federation

2017

19072018

048188

2018

Житкова Ю.В., Хасанова Д.Р.

Zhitkova Y.V., Hasanova D.R.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://www.bekhterevreview.com/jour/article/view/115

На небольшой популяции пациентов среднего и пожилого возраста с депрессией, развившейся на фоне хронической ишемии головного мозга, исследовано действие вортиоксетина (Бринтелликс) на состояние когнитивных функций и симптомы депрессии. Пациенты принимали вортиоксетин в дозе 10 мг в течение 6 месяцев. Вортиоксетин одинаково хорошо устранял когнитивную дисфункцию и депрессивную симптоматику у пациентов обеих возрастных групп. Когнитивная ремиссия, а также отсутствие рецидива депрессии сохранялись на протяжении 6 месяцев после отмены терапии. Вортиоксетин показал хорошую переносимость и безопасность на исследуемой популяции больных.

The effect of Vortioxetine (Brintellix) on the condition of cognitive functions and depression symptoms has been studied on a small population of middle aged and elderly patients with depression developed on the background of chronical brain ischemia. Patients were taking Vortioxetine in the dose of 10 mg during 6 months. Vortioxetine eliminated both cognitive dysfunction and symptoms of depression in patients of both age groups. Cognitive remission as well as absence of relapses continued within 6 months after medication cancellation. Vortioxetine showed a good acceptability and safety in the study population.

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The authors declare that there are no conflicts of interest present.