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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">bekhterev</journal-id><journal-title-group><journal-title xml:lang="ru">Обозрение психиатрии и медицинской психологии имени В.М.Бехтерева</journal-title><trans-title-group xml:lang="en"><trans-title>V.M. BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2313-7053</issn><issn pub-type="epub">2713-055X</issn><publisher><publisher-name>V. M. BEKHTEREV  NATIONAL  RESEARCH  MEDICAL  CENTER  FOR  PSYCHIATRY  AND  NEUROLOGY                           OF    THE  RUSSIAN  FEDERATION   MINISTRY  OF  HEALTH</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">bekhterev-119</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>В ПОМОЩЬ ПРАКТИКУЮЩЕМУ ВРАЧУ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>GUIDELINES FOR THE PRACTITIONER</subject></subj-group></article-categories><title-group><article-title>Стратификация риска развития поздних лекарственно-индуцированных осложнений</article-title><trans-title-group xml:lang="en"><trans-title>Stratification of the risk of developing tardive drug-induced complications</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Михайлов</surname><given-names>Владимир Алексеевич</given-names></name><name name-style="western" xml:lang="en"><surname>Khublarova</surname><given-names>L. A.</given-names></name></name-alternatives><email xlink:type="simple">vladmikh@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Захаров</surname><given-names>Денис Валерьевич</given-names></name><name name-style="western" xml:lang="en"><surname>Zakharov</surname><given-names>D. V.</given-names></name></name-alternatives><email xlink:type="simple">zaharov_dv@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хубларова</surname><given-names>Ливия Артуровна</given-names></name><name name-style="western" xml:lang="en"><surname>Mikhaylov</surname><given-names>V. A.</given-names></name></name-alternatives><email xlink:type="simple">liviya_a@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Национальный медицинский исследовательский центр психиатрии и неврологии им. В.М. Бехтерева»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.M. Bekhterev national research medical center for psychiatry and neurology</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>19</day><month>07</month><year>2018</year></pub-date><volume>0</volume><issue>4</issue><fpage>111</fpage><lpage>114</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Михайлов В.А., Захаров Д.В., Хубларова Л.А., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Михайлов В.А., Захаров Д.В., Хубларова Л.А.</copyright-holder><copyright-holder xml:lang="en">Khublarova L.A., Zakharov D.V., Mikhaylov V.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.bekhterevreview.com/jour/article/view/119">https://www.bekhterevreview.com/jour/article/view/119</self-uri><abstract><p>Поздняя лекарственная дистония/дискинезия - одна из наиболее редких, и, вместе с тем, наиболее тяжелых двигательных осложнений, связанных с приемом фармакологических препаратов. Комплексная оценка факторов риска развития поздних лекарственно-индуцированных побочных эффектов позволяет, учитывая их, более рационально подходить к выбору терапии, повышая уровень эффективности и безопасности реабилитационного процесса.</p></abstract><trans-abstract xml:lang="en"><p>Tardive drug dystonia / dyskinesia is one of the rare, and at the same time, the most severe motor complications associated with the use of pharmacological drugs. Complex assessment of risk factors for the development of tardive drug-induced side effects makes it possible to take a more rational approach for the target therapy, to make rehabilitation more effective and safe.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>поздние лекарственно-индуцированные дискинезии</kwd><kwd>обмен дофами</kwd><kwd>факторы риска</kwd><kwd>tardive drug-induced dyskinesias</kwd><kwd>dopamine metabolism</kwd><kwd>risk factors</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Бойко А.С. Клинико-биологические особенности тардивной дискинезии у больных шизофренией на фоне длительной антипсихотической терапи. Диссертация на соискание ученой степени кандидата медицинских наук. - 2016. - 2016. - С. 38-40.</mixed-citation><mixed-citation xml:lang="en">Бойко А.С. 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