<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">bekhterev</journal-id><journal-title-group><journal-title xml:lang="ru">Обозрение психиатрии и медицинской психологии имени В.М.Бехтерева</journal-title><trans-title-group xml:lang="en"><trans-title>V.M. BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2313-7053</issn><issn pub-type="epub">2713-055X</issn><publisher><publisher-name>V. M. BEKHTEREV  NATIONAL  RESEARCH  MEDICAL  CENTER  FOR  PSYCHIATRY  AND  NEUROLOGY                           OF    THE  RUSSIAN  FEDERATION   MINISTRY  OF  HEALTH</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31363/2313-7053-2025-4-2-1137</article-id><article-id custom-type="elpub" pub-id-type="custom">bekhterev-1246</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НАУЧНЫЕ ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>SCIENTIFIC REVIEW</subject></subj-group></article-categories><title-group><article-title>Суицидальное поведение у пациентов с шизофренией (нарративный обзор)</article-title><trans-title-group xml:lang="en"><trans-title>Suicidal behavior in patients with schizophrenia (narrative review)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3405-0407</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мунин</surname><given-names>А. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Munin</surname><given-names>A. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мунин Андрей Олегович - врач-психиатр; аспирант</p><p>107076, г. Москва, ул. Потешная, 3;</p><p>115522, г. Москва, ул. Каширское шоссе, 34</p></bio><bio xml:lang="en"><p>Andrei O. Munin</p><p>Moscow</p></bio><email xlink:type="simple">Munin1@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0021-4936</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Голубев</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Golubev</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Голубев Сергей Александрович - д.м.н., заместитель главного врача по медицинской части; ведущий научный сотрудник</p><p>107076, г. Москва, ул. Потешная, 3;</p><p>115522, г. Москва, ул. Каширское шоссе, 34</p></bio><bio xml:lang="en"><p>Sergey A. Golubev </p><p>Moscow</p></bio><email xlink:type="simple">color1982@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Психиатрическая клиническая больница № 4 им. П. Б. Ганнушкина Департамента здравоохранения города Москвы; Научный центр психического здоровья</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Psychiatric Clinical Hospital 4 named after P.B. Gannushkin; Mental Health Research Center</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>10</day><month>01</month><year>2026</year></pub-date><volume>59</volume><issue>4-2</issue><fpage>30</fpage><lpage>37</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мунин А.О., Голубев С.А., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Мунин А.О., Голубев С.А.</copyright-holder><copyright-holder xml:lang="en">Munin A.O., Golubev S.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.bekhterevreview.com/jour/article/view/1246">https://www.bekhterevreview.com/jour/article/view/1246</self-uri><abstract><p>Статья представляет собой нарративный обзор литературы, в котором комплексно рассматривается проблема суицидального поведения у пациентов с шизофренией. В данной статье описаны факторы риска, методы профилактики и лечения суицидального поведения у пациентов с шизофренией. Суицид — одна из ведущих причин преждевременной смерти среди пациентов с шизофренией, значительно снижающая среднюю продолжительность жизни у данной категории пациентов. Уровень риска суицида при шизофрении значительно выше, чем в общей популяции. Наибольший риск суицидального поведения приходится на первые годы после дебюта заболевания, однако он сохраняется на протяжении всей жизни. Ключевыми факторами суицидального риска является мужской пол, молодой возраст, депрессия, злоупотребление психоактивными веществами, соматическая коморбидная патология и социальная изоляция и др. Для адекватной оценки суицидального риска требуется тщательная верификация факторов риска. Современные подходы к этой проблеме ориентированы  на  комплексную  оценку  факторов  риска,  с  использованием персонализированного подхода, учитывающего субъективно значимые аспекты для пациента. Основные цели терапии включают выявление пациентов из группы риска, снижение модифицируемых факторов и предотвращение событий, увеличивающих суицидальность, при активном использовании защитных факторов. Высокая распространенность суицидального поведения среди данной группы пациентов делает проблему актуальной для клинической практики и системы здравоохранения. Важную роль играют психосоциальные интервенции, включая меры по повышению приверженности к терапии, психообразовательные программы для пациентов, персонала и родственников пациентов, а также семейная терапия. Для эффективного лечения и профилактики данной группы пациентов необходим комплексный подход, включающий психосоциальные вмешательства и применение современных медикаментозных методов.</p></abstract><trans-abstract xml:lang="en"><p>The article is a narrative review of the literature that comprehensively examines the problem of suicidal behavior in patients with schizophrenia. This article describes the risk factors, methods of prevention and treatment of suicidal behavior in patients with schizophrenia. Suicide is one of the leading causes of premature death among patients with schizophrenia, significantly reducing the average life expectancy in this category of patients. The risk of suicide in schizophrenia is significantly higher than in the general population. The highest risk of suicidal behavior occurs in the first years after the onset of the disease, but it persists throughout life. The key factors of suicide risk are male gender, young age, depression, substance abuse, somatic comorbid pathology and social isolation, etc.</p><p>Adequate assessment of suicide risk requires careful verification of risk factors. Modern approaches to this problem are focused on a comprehensive assessment of risk factors, using a personalized approach that takes into account subjectively significant aspects for the patient. The main goals of therapy include identifying patients at risk, reducing modifiable factors, and preventing events that increase suicidality with active use of protective factors. The high prevalence of suicidal behavior among this group of patients makes the problem relevant for clinical practice and the health care system. Psychosocial interventions play an important role, including measures to increase adherence to therapy, psychoeducational programs for patients, staff, and relatives of patients, as well as family therapy. For effective treatment and prevention of this group of patients, a comprehensive approach is needed, including psychosocial interventions and the use of modern drug methods.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>cуицидальное поведение</kwd><kwd>шизофрения</kwd><kwd>факторы риска</kwd><kwd>суицид</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Suicidal behavior</kwd><kwd>schizophrenia</kwd><kwd>risk factors</kwd><kwd>suicide</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Айрапетян А.А., Бурак Е.С., Умаров А.Х., Колесникова Ю.А. Самоубийство при шизофрении. Научные исследования высшей школы: Сборник статей VII Международной научно-практической конференции, Пенза, 27 января 2022 года. – Пенза: Наука и Просвещение, 2022.</mixed-citation><mixed-citation xml:lang="en">Ajrapetyan A.A., Burak E.S., Umarov A.H., Kolesnikova Yu.A. Samoubijstvo pri shizofrenii. Nauchnye issledovaniya vysshej shkoly: Sbornik statej VII Mezhdunarodnoj nauchno-prakticheskoj konferencii, Penza, 27 yanvarya 2022 goda. – Penza: Nauka i Prosveshchenie, 2022. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Амбрумова А.Г., Тихоненко В.А. Диагностика суицидального поведения: Методические рекомендации. – М., 1980.</mixed-citation><mixed-citation xml:lang="en">Ambrumova A.G., Tihonenko V.A. Diagnostika suicidal'nogo povedeniya: Metodicheskie rekomendacii. – M., 1980. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Любов Е.Б. Факторы риска суицидального поведения больных шизофренией. Российский психиатрический журнал. 2018;4:24-30. http://dx.doi.org/10.24411/1560-957X-2018-1%25x</mixed-citation><mixed-citation xml:lang="en">Lyubov EB. Risk factors of suicidal behavior in patients with schizophrenia. Rossiyskiy Psikhiatricheskiy Zhurnal. 2018;4:24-30. (In Russ.). http://dx.doi.org/10.24411/1560-957X-2018-1%25x</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Мосолов С.Н. Диагностика и терапия депрессии при шизофрении. Consortium Psychiatricum. 2020;1(2):29-42. https://doi.org/10.17650/2712-7672-2020-1-2-29-42.</mixed-citation><mixed-citation xml:lang="en">Mosolov SN. Diagnosis and therapy of depression in schizophrenia. Consortium Psychiatricum. 2020;1(2):29-42. (In Russ.). https://doi.org/10.17650/2712-7672-2020-1-2-29-42.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Петрова Н.Н. Факторы риска и превенция суицида при шизофрении: фокус на роли современных инъекционных антипсихотиков-пролонгов. Современная терапия психических расстройств. 2021;3:31-37. https://doi.org/10.21265/PSYPH.2021.15.71.003</mixed-citation><mixed-citation xml:lang="en">Petrova NN. Risk factors and prevention of suicide in schizophrenia: focus on the role of modern long-acting injectable antipsychotics. Sovremennaya Terapiya Psikhicheskikh Rasstroystv. 2021;3:31-37. (In Russ.). https://doi.org/10.21265/PSYPH.2021.15.71.003</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Положий Б.С. Интегративная модель суицидального поведения. Российский психиатрический журнал. 2010;4:55-62.</mixed-citation><mixed-citation xml:lang="en">Polozhy BS. Integrative model of suicidal behavior. Rossiyskiy Psikhiatricheskiy Zhurnal. 2010;4:55-62. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Симак О.Я. Проблема суицида при шизофрении: в фокусе внимания семья больного (обзор литературы). Суицидология. 2018;9(4):17-28. https://doi.org/10.32878/suiciderus.18-09-04(33)-17-28</mixed-citation><mixed-citation xml:lang="en">Simak OYa. The problem of suicide in schizophrenia: the family of the patient is in focus (literature review). Suitsidologiya. 2018;9(4):17-28. (In Russ.). https://doi.org/10.32878/suiciderus.18-09-04(33)-17-28</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Altamura AC, Bassetti R, Bignotti S, et al. Clinical variables related to suicide attempts in schizophrenic patients: a retrospective study. Schizophr Res. 2003;60:47–55. https://doi.org/10.1016/s0920-9964(02)00164-0.</mixed-citation><mixed-citation xml:lang="en">Altamura AC, Bassetti R, Bignotti S, et al. Clinical variables related to suicide attempts in schizophrenic patients: a retrospective study. Schizophr Res. 2003;60:47–55. https://doi.org/10.1016/s0920-9964(02)00164-0.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Berardelli I, Rogante E, Sarubbi S, Erbuto D, Lester D, Pompili M. The Importance of Suicide Risk Formulation in Schizophrenia. Front. Psychiatry. 2021;12:779684. https://doi.org/10.3389/fpsyt.2021.779684</mixed-citation><mixed-citation xml:lang="en">Berardelli I, Rogante E, Sarubbi S, Erbuto D, Lester D, Pompili M. The Importance of Suicide Risk Formulation in Schizophrenia. Front. Psychiatry. 2021;12:779684. https://doi.org/10.3389/fpsyt.2021.779684</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Bornheimer LA, Zhang A, Li J, Hiller M, Tarrier N. Effectiveness of Suicide-Focused Psychosocial Interventions in Psychosis: A Systematic Review and Meta-Analysis. Psychiatr Serv. 2020;71(8):829-838. https://doi.org/10.1176/appi.ps.201900487</mixed-citation><mixed-citation xml:lang="en">Bornheimer LA, Zhang A, Li J, Hiller M, Tarrier N. Effectiveness of Suicide-Focused Psychosocial Interventions in Psychosis: A Systematic Review and Meta-Analysis. Psychiatr Serv. 2020;71(8):829-838. https://doi.org/10.1176/appi.ps.201900487</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Cipriani A, Pretty H, Hawton K, et al. Lithium in the prevention of suicidal behaviour and all-cause mortality in patients with mood disorders: a systematic review of randomized trials. Am J Psychiatry. 2005;162:1805–1819. https://doi.org/10.1176/appi.ajp.162.10.1805.</mixed-citation><mixed-citation xml:lang="en">Cipriani A, Pretty H, Hawton K, et al. Lithium in the prevention of suicidal behaviour and all-cause mortality in patients with mood disorders: a systematic review of randomized trials. Am J Psychiatry. 2005;162:1805–1819. https://doi.org/10.1176/appi.ajp.162.10.1805.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Correll CU, Solmi M, Croatto G, Schneider LK, Rohani-Montez SC, Fairley L, Smith N, Bitter I, Gorwood P, Taipale H, Tiihonen J. Mortality in people with schizophrenia: a systematic review and meta-analysis of relative risk and aggravating or attenuating factors. World Psychiatry. 2022;21:248-271. https://doi.org/10.1002/wps.20994</mixed-citation><mixed-citation xml:lang="en">Correll CU, Solmi M, Croatto G, Schneider LK, Rohani-Montez SC, Fairley L, Smith N, Bitter I, Gorwood P, Taipale H, Tiihonen J. Mortality in people with schizophrenia: a systematic review and meta-analysis of relative risk and aggravating or attenuating factors. World Psychiatry. 2022;21:248-271. https://doi.org/10.1002/wps.20994</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">De Berardis D, Rapini G, Olivieri L, et al. Safety of antipsychotics for the treatment of schizophrenia: a focus on the adverse effects of clozapine. Ther Adv Drug Saf. 2018;9(5):237-256. https://doi.org/10.1177/2042098618756261</mixed-citation><mixed-citation xml:lang="en">De Berardis D, Rapini G, Olivieri L, et al. Safety of antipsychotics for the treatment of schizophrenia: a focus on the adverse effects of clozapine. Ther Adv Drug Saf. 2018;9(5):237-256. https://doi.org/10.1177/2042098618756261</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Demir S. The relationship between expressed emotion and the probability of suicide among Turkish psychiatric outpatients: A descriptive cross-sectional survey. Fam. Community Health. 2018;41:111–116. https://doi.org/10.1097/FCH.0000000000000178.</mixed-citation><mixed-citation xml:lang="en">Demir S. The relationship between expressed emotion and the probability of suicide among Turkish psychiatric outpatients: A descriptive cross-sectional survey. Fam. Community Health. 2018;41:111–116. https://doi.org/10.1097/FCH.0000000000000178.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Díaz-Fernández S, Frías-Ortiz DF, Fernández-Miranda JJ. Suicide attempts in people with schizophrenia before and after participating in an intensive case managed community program: A 20-year follow-up. Psychiatry Res. 2020;287:112479. https://doi.org/10.1016/j.psychres.2019.112479</mixed-citation><mixed-citation xml:lang="en">Díaz-Fernández S, Frías-Ortiz DF, Fernández-Miranda JJ. Suicide attempts in people with schizophrenia before and after participating in an intensive case managed community program: A 20-year follow-up. Psychiatry Res. 2020;287:112479. https://doi.org/10.1016/j.psychres.2019.112479</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Gentile A, Bonfitto I, Stella E, Mari M, Steardo L, Bellomo A, Ventriglio A. Cуицидальное поведение в дебюте шизофрении. Суицидология. 2017;8-2(27):20-27. (In Russ.).</mixed-citation><mixed-citation xml:lang="en">Gentile A, Bonfitto I, Stella E, Mari M, Steardo L, Bellomo A, Ventriglio A. Cуицидальное поведение в дебюте шизофрении. Суицидология. 2017;8-2(27):20-27. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Guo X, Zhai J, Liu Z, et al. Effect of antipsychotic medication alone vs combined with psychosocial intervention on outcomes of early-stage schizophrenia: A randomized, 1-year study. Arch Gen Psychiatry. 2010;67(9):895-904. https://doi.org/10.1001/archgenpsychiatry.2010.105</mixed-citation><mixed-citation xml:lang="en">Guo X, Zhai J, Liu Z, et al. Effect of antipsychotic medication alone vs combined with psychosocial intervention on outcomes of early-stage schizophrenia: A randomized, 1-year study. Arch Gen Psychiatry. 2010;67(9):895-904. https://doi.org/10.1001/archgenpsychiatry.2010.105</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Gut-Fayand A, Dervaux A, Olie JP, et al. Substance abuse and suicidality in schizophrenia: a common risk factor linked to impulsivity. Psychiatry Res. 2001;102:65–72. https://doi.org/10.1016/s0165-1781(01)00250-5.</mixed-citation><mixed-citation xml:lang="en">Gut-Fayand A, Dervaux A, Olie JP, et al. Substance abuse and suicidality in schizophrenia: a common risk factor linked to impulsivity. Psychiatry Res. 2001;102:65–72. https://doi.org/10.1016/s0165-1781(01)00250-5.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Hodé Y, Dubreucq J, Valladier E, et al. Prévention du risque suicidaire dans la schizophrénie : importance de la psychoéducation des familles. Encephale. 2020;46(6):450-454. https://doi.org/10.1016/j.encep.2020.02.002</mixed-citation><mixed-citation xml:lang="en">Hodé Y, Dubreucq J, Valladier E, et al. Prévention du risque suicidaire dans la schizophrénie : importance de la psychoéducation des familles. Encephale. 2020;46(6):450-454. https://doi.org/10.1016/j.encep.2020.02.002</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Hor K, Taylor M. Suicide and schizophrenia: A systematic review of rates and risk factors. J. Psychopharmacol. 2010;24:81–90.</mixed-citation><mixed-citation xml:lang="en">Hor K, Taylor M. Suicide and schizophrenia: A systematic review of rates and risk factors. J. Psychopharmacol. 2010;24:81–90.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Kasckow J, Felmet K, Zisook S. Managing suicide risk in patients with schizophrenia. CNS Drugs. 2011;25(2):129-43. https://doi.org/10.2165/11586450-000000000-00000</mixed-citation><mixed-citation xml:lang="en">Kasckow J, Felmet K, Zisook S. Managing suicide risk in patients with schizophrenia. CNS Drugs. 2011;25(2):129-43. https://doi.org/10.2165/11586450-000000000-00000</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Leucht S, Kissling W, McGrath J. Lithium for schizophrenia. Cochrane Database Syst Rev. 2007;(3):CD003834. https://doi.org/10.1002/14651858.CD003834.pub2.</mixed-citation><mixed-citation xml:lang="en">Leucht S, Kissling W, McGrath J. Lithium for schizophrenia. Cochrane Database Syst Rev. 2007;(3):CD003834. https://doi.org/10.1002/14651858.CD003834.pub2.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Masdrakis VG, Baldwin DS. Prevention of suicide by clozapine in mental disorders: systematic review. Eur Neuropsychopharmacol. 2023;69:4-23. https://doi.org/10.1016/j.euroneuro.2022.12.011</mixed-citation><mixed-citation xml:lang="en">Masdrakis VG, Baldwin DS. Prevention of suicide by clozapine in mental disorders: systematic review. Eur Neuropsychopharmacol. 2023;69:4-23. https://doi.org/10.1016/j.euroneuro.2022.12.011</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Meltzer H. Suicide in schizophrenia: clozapine, the adoption of evidence-based medicine [commentary]. J Clin Psychiatry. 2005;66:4. https://doi.org/10.4088/jcp.v66n0417.</mixed-citation><mixed-citation xml:lang="en">Meltzer H. Suicide in schizophrenia: clozapine, the adoption of evidence-based medicine [commentary]. J Clin Psychiatry. 2005;66:4. https://doi.org/10.4088/jcp.v66n0417.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Meltzer HY, Alphs L, Green AI, et al. Clozapine treatment for suicidality in schizophrenia: International Suicide Prevention Trial (InterSePT). Arch Gen Psychiatry. 2003;60(1):82–91. https://doi.org/10.1001/archpsyc.60.1.82.</mixed-citation><mixed-citation xml:lang="en">Meltzer HY, Alphs L, Green AI, et al. Clozapine treatment for suicidality in schizophrenia: International Suicide Prevention Trial (InterSePT). Arch Gen Psychiatry. 2003;60(1):82–91. https://doi.org/10.1001/archpsyc.60.1.82.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Napa W, Tungpunkom P, Pothimas N. Effectiveness of family interventions on psychological distress and expressed emotion in family members of individuals diagnosed with first-episode psychosis: A systematic review. JBI Database Syst. Rev. Implement. Rep. 2017;15:1057–1079. https://doi.org/10.11124/JBISRIR-2017-003361.</mixed-citation><mixed-citation xml:lang="en">Napa W, Tungpunkom P, Pothimas N. Effectiveness of family interventions on psychological distress and expressed emotion in family members of individuals diagnosed with first-episode psychosis: A systematic review. JBI Database Syst. Rev. Implement. Rep. 2017;15:1057–1079. https://doi.org/10.11124/JBISRIR-2017-003361.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Onwumere J, Bebbington P, Kuipers E. Family interventions in early psychosis: Specificity and effectiveness. Epidemiol. Psychiatr. Sci. 2011;20:113–119. https://doi.org/10.1017/S2045796011000187.</mixed-citation><mixed-citation xml:lang="en">Onwumere J, Bebbington P, Kuipers E. Family interventions in early psychosis: Specificity and effectiveness. Epidemiol. Psychiatr. Sci. 2011;20:113–119. https://doi.org/10.1017/S2045796011000187.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Palmer DD, Henter ID, Wyatt RJ. Do antipsychotic medications decrease the risk of suicide in patients with schizophrenia? J Clin Psychiatry. 1999;60,Suppl.2:100–103;discussion 111–6.</mixed-citation><mixed-citation xml:lang="en">Palmer DD, Henter ID, Wyatt RJ. Do antipsychotic medications decrease the risk of suicide in patients with schizophrenia? J Clin Psychiatry. 1999;60,Suppl.2:100–103;discussion 111–6.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Peritogiannis V, Ninou A, Samakouri M. Mortality in Schizophrenia Spectrum Disorders: Recent Advances in Understanding and Management. Healthcare (Basel). 2022;10(12):2366. https://doi.org/10.3390/healthcare10122366</mixed-citation><mixed-citation xml:lang="en">Peritogiannis V, Ninou A, Samakouri M. Mortality in Schizophrenia Spectrum Disorders: Recent Advances in Understanding and Management. Healthcare (Basel). 2022;10(12):2366. https://doi.org/10.3390/healthcare10122366</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Pharoah F, Mari J, Rathbone J, Wong W. Family intervention for schizophrenia. Cochrane Database Syst Rev. 2010;(12):CD000088. https://doi.org/10.1002/14651858.CD000088.pub2</mixed-citation><mixed-citation xml:lang="en">Pharoah F, Mari J, Rathbone J, Wong W. Family intervention for schizophrenia. Cochrane Database Syst Rev. 2010;(12):CD000088. https://doi.org/10.1002/14651858.CD000088.pub2</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Pisani AR, Murrie DC, Silverman MM. Reformulating Suicide Risk Formulation: From Prediction to Prevention. Acad Psychiatry. 2016 Aug;40(4):623-9. https://doi.org/10.1007/s40596-015-0434-6</mixed-citation><mixed-citation xml:lang="en">Pisani AR, Murrie DC, Silverman MM. Reformulating Suicide Risk Formulation: From Prediction to Prevention. Acad Psychiatry. 2016 Aug;40(4):623-9. https://doi.org/10.1007/s40596-015-0434-6</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Pompili M, Amador XF, Girardi P, et al. Suicide risk in schizophrenia: learning from the past to change the future. Ann Gen Psychiatry. 2007;6:10. https://doi.org/10.1186/1744-859X-6-10</mixed-citation><mixed-citation xml:lang="en">Pompili M, Amador XF, Girardi P, et al. Suicide risk in schizophrenia: learning from the past to change the future. Ann Gen Psychiatry. 2007;6:10. https://doi.org/10.1186/1744-859X-6-10</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Pompili M, Orsolini L, Lamis D.A, Goldsmith DR, Nardella A, Falcone G, Corigliano V, Luciano M, Fiorillo A. Suicide prevention in schizophrenia: Do long-acting injectable antipsychotics (LAIs) have a role? CNS Neurol. Disord. Drug Targets. 2017;16:454–462. https://doi.org/10.2174/1871527316666170223163629.</mixed-citation><mixed-citation xml:lang="en">Pompili M, Orsolini L, Lamis D.A, Goldsmith DR, Nardella A, Falcone G, Corigliano V, Luciano M, Fiorillo A. Suicide prevention in schizophrenia: Do long-acting injectable antipsychotics (LAIs) have a role? CNS Neurol. Disord. Drug Targets. 2017;16:454–462. https://doi.org/10.2174/1871527316666170223163629.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Pompili M., Tatarelli C., Kotzalidis G.D., Tatarelli R. Suicide risk in substance abusers with schizophrenia. In R. Tatarelli, M. Pompili, P. Girardi (Eds.). Suicide in schizophrenia. - Nova Biomedical Books, 2007.</mixed-citation><mixed-citation xml:lang="en">Pompili M., Tatarelli C., Kotzalidis G.D., Tatarelli R. Suicide risk in substance abusers with schizophrenia. In R. Tatarelli, M. Pompili, P. Girardi (Eds.). Suicide in schizophrenia. - Nova Biomedical Books, 2007.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Sands JR, Harrow M. Depression During the Longitudinal Course of Schizophrenia. Schizophrenia Bulletin. 1999;25(1):157–72.</mixed-citation><mixed-citation xml:lang="en">Sands JR, Harrow M. Depression During the Longitudinal Course of Schizophrenia. Schizophrenia Bulletin. 1999;25(1):157–72.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Schenkel LS, Spaulding WD, DiLillo D, Silverstein SM. Histories of childhood maltreatment in schizophrenia: relationships with premorbid functioning, symptomatology, and cognitive deficits. Schizophr Res. 2005;76(2-3):273-86. https://doi.org/10.1016/j.schres.2005.03.003.</mixed-citation><mixed-citation xml:lang="en">Schenkel LS, Spaulding WD, DiLillo D, Silverstein SM. Histories of childhood maltreatment in schizophrenia: relationships with premorbid functioning, symptomatology, and cognitive deficits. Schizophr Res. 2005;76(2-3):273-86. https://doi.org/10.1016/j.schres.2005.03.003.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Schooler NR. Relapse prevention and recovery in the treatment of schizophrenia. J Clin Psychiatry. 2006;67,Suppl.5:19–23.</mixed-citation><mixed-citation xml:lang="en">Schooler NR. Relapse prevention and recovery in the treatment of schizophrenia. J Clin Psychiatry. 2006;67,Suppl.5:19–23.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Sher L, Kahn RS. Suicide in Schizophrenia: An Educational Overview. Medicina (Kaunas). 2019;55(7):361. https://doi.org/10.3390/medicina55070361</mixed-citation><mixed-citation xml:lang="en">Sher L, Kahn RS. Suicide in Schizophrenia: An Educational Overview. Medicina (Kaunas). 2019;55(7):361. https://doi.org/10.3390/medicina55070361</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Tandon R, Jibson MD. Suicidal behavior in schizophrenia: diagnosis, neurobiology, and treatment implications. Curr Opin Psychiatry. 2003;16:193–197.</mixed-citation><mixed-citation xml:lang="en">Tandon R, Jibson MD. Suicidal behavior in schizophrenia: diagnosis, neurobiology, and treatment implications. Curr Opin Psychiatry. 2003;16:193–197.</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Ventriglio A, Ricci F, Magnifico G, et al. Psychosocial interventions in schizophrenia: Focus on guidelines. Int J Soc Psychiatry. 2020;66(8):735-747. https://doi.org/10.1177/0020764020934827</mixed-citation><mixed-citation xml:lang="en">Ventriglio A, Ricci F, Magnifico G, et al. Psychosocial interventions in schizophrenia: Focus on guidelines. Int J Soc Psychiatry. 2020;66(8):735-747. https://doi.org/10.1177/0020764020934827</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Yiu HW, Rowe S, Wood L. A systematic review and meta-analysis of psychosocial interventions aiming to reduce risks of suicide and self-harm in psychiatric inpatients. Psychiatry Res. 2021;305:114175. https://doi.org/10.1016/j.psychres.2021.114175</mixed-citation><mixed-citation xml:lang="en">Yiu HW, Rowe S, Wood L. A systematic review and meta-analysis of psychosocial interventions aiming to reduce risks of suicide and self-harm in psychiatric inpatients. Psychiatry Res. 2021;305:114175. https://doi.org/10.1016/j.psychres.2021.114175</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
