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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">bekhterev</journal-id><journal-title-group><journal-title xml:lang="ru">Обозрение психиатрии и медицинской психологии имени В.М.Бехтерева</journal-title><trans-title-group xml:lang="en"><trans-title>V.M. BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2313-7053</issn><issn pub-type="epub">2713-055X</issn><publisher><publisher-name>V. M. BEKHTEREV  NATIONAL  RESEARCH  MEDICAL  CENTER  FOR  PSYCHIATRY  AND  NEUROLOGY                           OF    THE  RUSSIAN  FEDERATION   MINISTRY  OF  HEALTH</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">bekhterev-27</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НАУЧНЫЕ ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>SCIENTIFIC REVIEW</subject></subj-group></article-categories><title-group><article-title>Расстройства биполярного спектра при эпилепсии</article-title><trans-title-group xml:lang="en"><trans-title>Bipolar affective disorders in epilepsy</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мазо</surname><given-names>Галина Элевна</given-names></name><name name-style="western" xml:lang="en"><surname>Mazo</surname><given-names>G. E.</given-names></name></name-alternatives><email xlink:type="simple">galina-mazo@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Липатова</surname><given-names>Людмила Валентиновна</given-names></name><name name-style="western" xml:lang="en"><surname>Lipatova</surname><given-names>L. V.</given-names></name></name-alternatives><email xlink:type="simple">epilepsy-net@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жуков</surname><given-names>Никита Эдуардович</given-names></name><name name-style="western" xml:lang="en"><surname>Zhukov</surname><given-names>N. E.</given-names></name></name-alternatives><email xlink:type="simple">doc@0x3.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ФГБУ «Санкт-Петербургский научно-исследовательский психоневрологический институт им. В.М. Бехтерева» МЗ РФ; СПбГУ</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-2"><institution>ФГБУ «Санкт-Петербургский научно-исследовательский психоневрологический институт им. В.М. Бехтерева» МЗ РФ</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>19</day><month>07</month><year>2018</year></pub-date><volume>0</volume><issue>3</issue><fpage>30</fpage><lpage>40</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мазо Г.Э., Липатова Л.В., Жуков Н.Э., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Мазо Г.Э., Липатова Л.В., Жуков Н.Э.</copyright-holder><copyright-holder xml:lang="en">Mazo G.E., Lipatova L.V., Zhukov N.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.bekhterevreview.com/jour/article/view/27">https://www.bekhterevreview.com/jour/article/view/27</self-uri><abstract><p>Взаимоотношения между расстройствами биполярного спектра и эпилепсией имеют очевидную коморбидность, схожие теоретические основы патогенеза и общие терапевтические подходы. При обоих заболеваниях отмечается высокий риск суицида, без лечения частота эпизодов биполярных аффективных расстройств (БАР) увеличивается, а светлые промежутки становятся короче, прогрессирование заболевания становится похожим на таковое у эпилепсии. Рассматриваются общие патофизиологические механизмы формирования эпилепсии и БАР и принципы лечения аффективных расстройств биполярного спектра у больных эпилепсией (БЭ).</p></abstract><trans-abstract xml:lang="en"><p>The relationship between bipolar affective disorders (BAD) and epilepsy have an obvious comorbidity, similar theoretical bases of pathogenesis and treatment approaches. In both diseases, there is a high risk of suicide without treatment, the frequency of episodes of BAD increases, and the lucid intervals become shorter, the progression of the disease is similar to one as for epilepsy. Discusses general pathophysiological mechanisms of epilepsy and BAD and treatment of affective disorders of the bipolar spectrum in patients with epilepsy.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>расстройства биполярного спектра</kwd><kwd>эпилепсия</kwd><kwd>депрессия</kwd><kwd>нормотимики</kwd><kwd>bipolar affective disorders</kwd><kwd>epilepsy</kwd><kwd>depression</kwd><kwd>mood stabilizers</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Воробьева О.В. Фармакотерапия эпилепсии, ассоциированной с депрессией. -Эффективная фармакотерапия. - 2013. - Т. 32. - С. 38-44.</mixed-citation><mixed-citation xml:lang="en">Воробьева О.В. 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