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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">bekhterev</journal-id><journal-title-group><journal-title xml:lang="ru">Обозрение психиатрии и медицинской психологии имени В.М.Бехтерева</journal-title><trans-title-group xml:lang="en"><trans-title>V.M. BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2313-7053</issn><issn pub-type="epub">2713-055X</issn><publisher><publisher-name>V. M. BEKHTEREV  NATIONAL  RESEARCH  MEDICAL  CENTER  FOR  PSYCHIATRY  AND  NEUROLOGY                           OF    THE  RUSSIAN  FEDERATION   MINISTRY  OF  HEALTH</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">bekhterev-35</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>В ПОМОЩЬ ПРАКТИКУЮЩЕМУ ВРАЧУ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>GUIDELINES FOR THE PRACTITIONER</subject></subj-group></article-categories><title-group><article-title>Риск-менеджмент метаболических нарушений при использовании антипсихотиков</article-title><trans-title-group xml:lang="en"><trans-title>Risk management of metabolic disorders in the use of antipsychotics</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мазо</surname><given-names>Галина Элевна</given-names></name><name name-style="western" xml:lang="en"><surname>Mazo</surname><given-names>G. E.</given-names></name></name-alternatives><email xlink:type="simple">galina-mazo@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кибитов</surname><given-names>Александр Олегович</given-names></name><name name-style="western" xml:lang="en"><surname>Kibitov</surname><given-names>A. O.</given-names></name></name-alternatives><email xlink:type="simple">druggen@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ФГБУ «СПб НИПНИ им. В.М. Бехтерева» Минздрава России; СПбГУ</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-2"><institution>ФГБУ «ФМИЦПН им. В.П. Сербского» Минздрава России</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>19</day><month>07</month><year>2018</year></pub-date><volume>0</volume><issue>3</issue><fpage>85</fpage><lpage>97</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мазо Г.Э., Кибитов А.О., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Мазо Г.Э., Кибитов А.О.</copyright-holder><copyright-holder xml:lang="en">Mazo G.E., Kibitov A.O.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.bekhterevreview.com/jour/article/view/35">https://www.bekhterevreview.com/jour/article/view/35</self-uri><abstract><p>Метаболические нарушения и связанные с ними сердечно-сосудистые заболевания и сахарный диабет 2 типа высоко распространены у пациентов с шизофренией. В статье проведен анализ связи риска формирования метаболических нарушений с генетическими факторами, поведенческими нарушениями, связанными с шизофренией, и используемой терапией. Уменьшение рисков развития обменных нарушений при использовании антипсихотической терапии связано с разработкой специализированных комплексных программ для создания условий своевременного выявления и коррекции метаболических дисфункций. Предложен комплексный подход к данной проблеме и представлена программа минимизации риска развития обменных нарушений.</p></abstract><trans-abstract xml:lang="en"><p>Cardio-metabolic risk factors and diabetes mellitus type 2 are highly prevalent in patients with schizophrenia. Decrease of metabolic risks associated with use of atypical antipsychotics is connected with the development of specialised programs. They can prevent and treat metabolic disorders. This article presents a comprehensive approach to the problem and proposes a solution to minimise the risk of metabolic disorders. The analysis dependence risk of formation of metabolic disorders with genetic factors, behavioral disorders, associated with schizophreniaand therapypresented in the article.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>метаболические нарушения</kwd><kwd>антипсихотики</kwd><kwd>индуцируемая антипсихотиками прибавка веса</kwd><kwd>терапевтический менеджмент</kwd><kwd>зипрасидон</kwd><kwd>adverse metabolic effects</kwd><kwd>antipsychotics</kwd><kwd>antipsychotic-inducedweightgain</kwd><kwd>therapeutic management</kwd><kwd>ziprasidone</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Горобец Л.Н. Изменение массы тела у больных шизофренией и шизоаффективным расстройством в условиях длительной терапии атипичными антипсихотиками / Л.Н. 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