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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">bekhterev</journal-id><journal-title-group><journal-title xml:lang="ru">Обозрение психиатрии и медицинской психологии имени В.М.Бехтерева</journal-title><trans-title-group xml:lang="en"><trans-title>V.M. BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2313-7053</issn><issn pub-type="epub">2713-055X</issn><publisher><publisher-name>V. M. BEKHTEREV  NATIONAL  RESEARCH  MEDICAL  CENTER  FOR  PSYCHIATRY  AND  NEUROLOGY                           OF    THE  RUSSIAN  FEDERATION   MINISTRY  OF  HEALTH</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">bekhterev-37</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>В ПОМОЩЬ ПРАКТИКУЮЩЕМУ ВРАЧУ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>GUIDELINES FOR THE PRACTITIONER</subject></subj-group></article-categories><title-group><article-title>Проблемы церебральной микроциркуляции как терапевтическая мишень</article-title><trans-title-group xml:lang="en"><trans-title>Problems of cerebral microcirculation as a therapeutic target</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Захаров</surname><given-names>Денис Валерьевич</given-names></name><name name-style="western" xml:lang="en"><surname>Zakharov</surname><given-names>D. V.</given-names></name></name-alternatives><email xlink:type="simple">zaharov_dv@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Михайлов</surname><given-names>Владимир Алексеевич</given-names></name><name name-style="western" xml:lang="en"><surname>Mikhailov</surname><given-names>V. A.</given-names></name></name-alternatives><email xlink:type="simple">vladmikh@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Санкт-Петербургский научно-исследовательский психоневрологический институт им. В.М. Бехтерева</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>19</day><month>07</month><year>2018</year></pub-date><volume>0</volume><issue>3</issue><fpage>103</fpage><lpage>108</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Захаров Д.В., Михайлов В.А., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Захаров Д.В., Михайлов В.А.</copyright-holder><copyright-holder xml:lang="en">Zakharov D.V., Mikhailov V.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.bekhterevreview.com/jour/article/view/37">https://www.bekhterevreview.com/jour/article/view/37</self-uri><abstract><p>В статье обсуждается проблема дисциркуляторной энцефалопатии (ДЭ) - хронической цереброваскулярной патологии, характеризующейся многоочаговым или диффузным поражением головного мозга и проявляющейся комплексом неврологических и нейропсихологических расстройств. Представлены сведения, касающиеся этиопатогенеза, морфологических и клинических проявлений заболевания, критерии диагностики и принципы лечения ДЭП. Авторы считают, что своевременная полноценная диагностика ДЭ позволяет обеспечить выбор адекватной тактики ведения больного, подбор комплексной терапии, охватывающей весь спектр патогенетических и клинических вариантов этого заболевания и обеспечивающей профилактику осложнений. Своевременное начало лечения позволяет не только улучшить качество жизни пациента, но и существенно продлить период его социальной активности.</p></abstract><trans-abstract xml:lang="en"><p>The problem of discirculatory encephalopathy(DE) - chronic cerebrovascular disease, characterized by multifocal or diffuse brain damage, and manifested a complex neurological and neuropsychological disorders. Presents information concerning the etiology and pathogenesis, morphological and clinical manifestations of the disease, diagnostic criteria and treatment guidelines vascular encephalopathy. The authors consider that modern complete diagnostics of discirculatory encephalopathy allows to implement an adequate tactics of treatment, to choose a complex therapy effective for all spectrum of pathogenetic and clinical variants of the disease as well as to provide prophylactics of DE complications. Timely treatment improves not only the patient’s quality of life but considerably prolongs the period of his active social activity.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>дисциркуляторная энцефалопатия</kwd><kwd>нарушения мозгового кровообращения</kwd><kwd>ницерголин</kwd><kwd>discirculatory encepalopathy</kwd><kwd>brain circulation disorders</kwd><kwd>nicergoline</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Балунов О.А., Захаров Д.В. Динамика показателей функционального состояния и качества жизни у пациентов с дисциркуляторной энцефалопатией в процессе лечения. - Обозрение психиатрии и медицинской психологии им. В. М. Бехтерева. - СПб., 2007. - № 2. - С. 12-16.</mixed-citation><mixed-citation xml:lang="en">Балунов О.А., Захаров Д.В. 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