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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">bekhterev</journal-id><journal-title-group><journal-title xml:lang="ru">Обозрение психиатрии и медицинской психологии имени В.М.Бехтерева</journal-title><trans-title-group xml:lang="en"><trans-title>V.M. BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2313-7053</issn><issn pub-type="epub">2713-055X</issn><publisher><publisher-name>V. M. BEKHTEREV  NATIONAL  RESEARCH  MEDICAL  CENTER  FOR  PSYCHIATRY  AND  NEUROLOGY                           OF    THE  RUSSIAN  FEDERATION   MINISTRY  OF  HEALTH</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31363/2313-7053-2021-1-60-66</article-id><article-id custom-type="elpub" pub-id-type="custom">bekhterev-536</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>INVESTIGATIONS</subject></subj-group></article-categories><title-group><article-title>Гендерные особенности влияния депрессивной и диссомнической симптоматики на показатели качества жизни больных псориазом</article-title><trans-title-group xml:lang="en"><trans-title>Gender features of the influence of depressive and dissominal symptoms on the quality of life of patients with psoriasis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2267-0956</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ольшевская</surname><given-names>Н. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Olshevskaya</surname><given-names>N. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Симферополь</p></bio><bio xml:lang="en"><p>Simferopol</p></bio><email xlink:type="simple">lshevskaya.natalya@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9290-3260</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ольшевский</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Olshevsky</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Симферополь</p></bio><bio xml:lang="en"><p>Simferopol</p></bio><email xlink:type="simple">olshievskii.nikita@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0754-7888</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Прохоров</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Prohorov</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Симферополь</p></bio><bio xml:lang="en"><p>Simferopol</p></bio><email xlink:type="simple">d_prokhorov@ukr.net</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8308-2037</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Клинков</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Klinkov</surname><given-names>V. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Симферополь</p></bio><bio xml:lang="en"><p>Simferopol</p></bio><email xlink:type="simple">klinkov.val@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3885-8534</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Примышева</surname><given-names>Е. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Primysheva</surname><given-names>H. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Симферополь</p></bio><bio xml:lang="en"><p>Simferopol</p></bio><email xlink:type="simple">primysheva.helen@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5339-1661</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сарачан</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sarachan</surname><given-names>D. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Симферополь</p></bio><bio xml:lang="en"><p>Simferopol</p></bio><email xlink:type="simple">sarachan.dmitriy@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4961-3249</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Куличенко</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Kulichenko</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Симферополь</p></bio><bio xml:lang="en"><p>Simferopol</p></bio><email xlink:type="simple">alexander.kulichenko@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3182-4286</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чинов</surname><given-names>С. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Chinov</surname><given-names>S. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Симферополь</p></bio><bio xml:lang="en"><p>Simferopol</p></bio><email xlink:type="simple">kru.kkvd@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное автономное образовательное учреждение высшего образования «Крымский федеральный университет имени В.И. Вернадского»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State Autonomous Educational Institution of Higher Education «V.I. Vernadsky Сrimean Federal University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Государственное бюджетное учреждение здравоохранения Республики Крым «Клинический кожно-венерологический диспансер»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State Budgetary Healthcare Institution of the Republic of Crimea «Clinical Dermatovenerologic Dispensary»</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>12</day><month>04</month><year>2021</year></pub-date><volume>55</volume><issue>1</issue><fpage>60</fpage><lpage>66</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ольшевская Н.С., Ольшевский Н.А., Прохоров Д.В., Клинков В.Н., Примышева Е.Н., Сарачан Д.А., Куличенко А.М., Чинов С.Г., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Ольшевская Н.С., Ольшевский Н.А., Прохоров Д.В., Клинков В.Н., Примышева Е.Н., Сарачан Д.А., Куличенко А.М., Чинов С.Г.</copyright-holder><copyright-holder xml:lang="en">Olshevskaya N.S., Olshevsky N.A., Prohorov D.V., Klinkov V.N., Primysheva H.N., Sarachan D.A., Kulichenko A.M., Chinov S.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.bekhterevreview.com/jour/article/view/536">https://www.bekhterevreview.com/jour/article/view/536</self-uri><abstract><p>Показатели качества жизни (КЖ) пациентов широко применяются в дерматологической практике, однако, недостаточно изучено влияние депрессивной и диссомнической симптоматики на КЖ больных с учетом половых различий.</p><sec><title>Цель</title><p>Цель: выявить депрессивную и диссомническую симптоматику у больных псориазом и оценить ее влияние на качество жизни (КЖ) больных с учетом гендерных различий.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Обследовано 34 пациента с псориазом. Исследование включало клинический и психодиагностический методы. Диагностику наличия и тяжести депрессии проводили с помощью шкалы оценки здоровья пациента PHQ-9. Диссомническую симптоматику у больных псориазом определяли с помощью индекса выраженности бессонницы ISI. Для оценки КЖ использовали дерматологический индекс качества жизни (DLQI).</p></sec><sec><title>Результаты и обсуждение</title><p>Результаты и обсуждение. Нарушения сна выявлены у 15 пациентов (44,1 %), депрессивная симптоматика определена у всех пациентов, негативное влияние заболевания на КЖ пациентов установлено у 32 человек (94,1 %). Корреляционный анализ данных позволил выявить статистически значимые корреляции показателя DLQI с выраженностью депрессивной симптоматики (r=0,45, p=0,008) и нарушений сна (r=0,35, p=0,04). У женщин показатель DLQI значимо коррелирует с выраженностью депрессии (r=0,48, p=0,04) и проявляет тенденцию к взаимосвязи с нарушениями сна (r=0,43, p=0,07). У мужчин связь DLQI с показателями уровня депрессии и нарушений сна существенно слабее и не является статистически значимой ((r=0,34, p=0,22) и (r=0,17, p=0,55), соответственно).</p></sec><sec><title>Заключение</title><p>Заключение. Депрессивная симптоматика и расстройства сна взаимосвязаны с КЖ больных псориазом, эта взаимосвязь более выражена у женщин. Воздействия, направленные на нормализацию настроения и сна, целесообразно включать в программу комплексной терапии псориаза, учитывая гендерные различия.</p></sec></abstract><trans-abstract xml:lang="en"><p>Quality of life indicators (QL) of patients are widely used in dermatological practice, but the influence of depressive and dissomnic symptoms on QL of patients with gender differences is not sufficiently studied.</p><sec><title>Objective</title><p>Objective: to identify depressive and dissominal symptoms in patients with psoriasis and evaluate its impact on the quality of life of these patients taking into account gender differences.</p></sec><sec><title>Materials and methods</title><p>Materials and methods: 34 patients with psoriasis were examined. Clinical examination included: analysis of complaints, medical history, assessment of dermatological status. Diagnosis of the presence and severity of depression was performed using a PHQ-9 patient health rating scale. Dissominal symptoms in patients with psoriasis were determined using the index of severity of insomnia ISI. To assess the quality of life, a dermatological index of quality of life (DLQI) was used.</p></sec><sec><title>Results and discussion</title><p>Results and discussion. Sleep disorders were detected in 15 patients (44.1%), depressive symptoms were determined in all patients, a negative effect of the disease on the quality of life of patients was found in 32 people (94.1%).Correlation analysis of data from the entire population of patients revealed statistically significant correlations of DLQI with the severity of depressive symptoms (r = 0.45, p = 0.008) and sleep disorders (r = 0.35, p = 0.04). In women, DLQI significantly correlates with the severity of depression (r = 0.48, p = 0.04) and tends to be associated with sleep disturbances (r = 0.43, p = 0.07). In men, the relationship between DLQI and indicators of depression and sleep disturbances is significantly weaker and is not statistically significant ((r = 0.34, p = 0.22) and (r = 0.17, p = 0.55), respectively).</p></sec><sec><title>Conclusion</title><p>Conclusion.depressive symptoms and sleep disorders are interrelated with the quality of life of patients with psoriasis, and this relationship is more pronounced in women. Consequently, it is advisable to include effects aimed at normalizing mood and sleep in the program of complex therapy of psoriasis, taking into account gender differences.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>псориаз</kwd><kwd>депрессия</kwd><kwd>нарушения сна</kwd><kwd>качество жизни</kwd></kwd-group><kwd-group xml:lang="en"><kwd>psoriasis</kwd><kwd>depression</kwd><kwd>sleep disorders</kwd><kwd>quality of life</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Гафаров В.В., Гагулин И.В., Громова Е.А. и др. Депрессия, тревога и нарушения сна у населения 45-69 лет в России (Сибирь): эпидемиологическое исследование. Неврология, нейропсихиатрия, психосоматика. 2017; 9(4):31-37. doi: 10.14412/2074-2711-2017-4-31-37</mixed-citation><mixed-citation xml:lang="en">Gafarov  VV,  Gagulin  IV,  Gromova  EA  et  al. 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