bekhterevОбозрение психиатрии и медицинской психологии имени В.М.БехтереваV.M. BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY2313-70532713-055XV. M. BEKHTEREV NATIONAL RESEARCH MEDICAL CENTER FOR PSYCHIATRY AND NEUROLOGY OF THE RUSSIAN FEDERATION MINISTRY OF HEALTHbekhterev-67Research ArticleВ ПОМОЩЬ ПРАКТИКУЮЩЕМУ ВРАЧУGUIDELINES FOR THE PRACTITIONERИнсомния на фоне зависимости от приема снотворных препаратовInsomnia due to hypnotic abuseПолуэктовМихаил ГурьевичPoluektovM. G.polouekt@mail.ruПчелинаПолина ВалерьевнаPchelinaP. V.noemail@neicon.ruГБОУ ВПО «Первый МГМУ им. И.М. Сеченова» Минздрава РоссииРоссияI.M. Sechenov Moscow State Medical UniversityRussian Federation201719072018017580Copyright © Полуэктов М.Г., Пчелина П.В., 20182018Полуэктов М.Г., Пчелина П.В.Poluektov M.G., Pchelina P.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.bekhterevreview.com/jour/article/view/67

Инсомния, ассоциированная со злоупотреблением и зависимостью от снотворных препаратов, является распространенной проблемой сомнологии вне зависимости от того, что было первично: нарушения сна или прием лекарств. Современные снотворные средства, представляющие собой агонисты бензодиазепиновых рецепторов, обладают более высоким профилем безопасности, чем снотворные первого поколения, однако имеются данные о развитии на фоне их приема зависимости и синдрома отмены. В структуре синдрома отмены наибольшую опасность представляют гемодинамические и респираторные нарушения, а также снижение порога судорожной готовности. Лечение зависимости от снотворных включает меры по детоксикации и постепенной замене снотворного на более безопасные методы лечения инсомнии.

Insomnia due to hypnotics abuse and dependence is a common and serious problem of somnology irrespectively of which one comes first: sleep disturbances or drug use. Modern hypnotics demonstrates selective affinity to some types of benzodiazepine receptors. This explains its higher safety profile than for first-generation hypnotics. Nevertheless there are reports of dependence and withdrawal syndrome associated with its administration as well. The most dangerous symptoms of withdrawal are seizures, hemodynamic and respiratory disturbances. Treatment of a hypnotic dependence includes detoxication and gradual withdrawal of medicines.

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The authors declare that there are no conflicts of interest present.