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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">bekhterev</journal-id><journal-title-group><journal-title xml:lang="ru">Обозрение психиатрии и медицинской психологии имени В.М.Бехтерева</journal-title><trans-title-group xml:lang="en"><trans-title>V.M. BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2313-7053</issn><issn pub-type="epub">2713-055X</issn><publisher><publisher-name>V. M. BEKHTEREV  NATIONAL  RESEARCH  MEDICAL  CENTER  FOR  PSYCHIATRY  AND  NEUROLOGY                           OF    THE  RUSSIAN  FEDERATION   MINISTRY  OF  HEALTH</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">bekhterev-81</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НАУЧНО-ИССЛЕДОВАТЕЛЬСКИЕ РАБОТЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>RESEARCH PAPERS</subject></subj-group></article-categories><title-group><article-title>Исследование клинического полиморфизма и качества жизни больных эссенциальным тремором</article-title><trans-title-group xml:lang="en"><trans-title>Study of clinical polymorphism and the quality of life of patients with essential tremor</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ярыгина</surname><given-names>Юлия Владимировна</given-names></name><name name-style="western" xml:lang="en"><surname>Iarygina</surname><given-names>Iu. V.</given-names></name></name-alternatives><email xlink:type="simple">judidu@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Захаров</surname><given-names>Денис Валерьевич</given-names></name><name name-style="western" xml:lang="en"><surname>Zaharov</surname><given-names>D. V.</given-names></name></name-alternatives><email xlink:type="simple">zaharov_dv@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Михайлов</surname><given-names>Владимир Алексеевич</given-names></name><name name-style="western" xml:lang="en"><surname>Mikhailov</surname><given-names>V. A.</given-names></name></name-alternatives><email xlink:type="simple">vladmikh@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Богачева</surname><given-names>Вероника Андреевна</given-names></name><name name-style="western" xml:lang="en"><surname>Bogacheva</surname><given-names>V. A.</given-names></name></name-alternatives><email xlink:type="simple">ronika1988@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хубларова</surname><given-names>Ливия Артуровна</given-names></name><name name-style="western" xml:lang="en"><surname>Hublarova</surname><given-names>L. A.</given-names></name></name-alternatives><email xlink:type="simple">liviya_a@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Санкт-Петербургский научно-исследовательский психоневрологический институт им. В.М. Бехтерева</institution><country>Россия</country></aff><aff xml:lang="en"><institution>The Saint-Petersburg V.M. Bekhterev Psychoneurological Research Institute</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>19</day><month>07</month><year>2018</year></pub-date><volume>0</volume><issue>2</issue><fpage>71</fpage><lpage>78</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ярыгина Ю.В., Захаров Д.В., Михайлов В.А., Богачева В.А., Хубларова Л.А., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Ярыгина Ю.В., Захаров Д.В., Михайлов В.А., Богачева В.А., Хубларова Л.А.</copyright-holder><copyright-holder xml:lang="en">Iarygina I.V., Zaharov D.V., Mikhailov V.A., Bogacheva V.A., Hublarova L.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.bekhterevreview.com/jour/article/view/81">https://www.bekhterevreview.com/jour/article/view/81</self-uri><abstract><p>Эссенциальный тремор (ЭТ) характеризуется неоднородностью и различной выраженностью тремора рук, который определяя степень функциональных нарушений, снижает качество жизни (КЖ) больных. Результаты: Выделены подгруппы пациентов, страдающих эссенциальным тремором, для которых характерны значимые различия по амплитуде тремора и его протяженности во времени. Первая подгруппа включает пациентов с преобладанием кинетического тремора над постуральным, представленным преимущественно асимметрично; вторая подгруппа характеризуется высокоамплитудным симметричным постурально-кинетическим тремором; третья подгруппа - низкоамплитудным постурально-кинетическим тремором. Тремор в наибольшей степени ограничивает ролевую деятельность при относительно сохранной способности к выполнению общих физических нагрузок. Для пациентов с ЭТ характерны средние и низкие оценки физического и психического компонентов КЖ. Более низко было оценено КЖ пациентами 2 подгруппы, а физический компонент здоровья в целом был выше у пациентов 3 группы, что сочеталось с меньшей протяженностью тремора во времени.</p></abstract><trans-abstract xml:lang="en"><p>Essential tremor (ET) is characterized by heterogeneity and variable intensity of hand tremor, which accounts for the severity of functional disorders, thus lowering the quality of life (QoL) of patients. Findings: As a result of the research, we have identified subgroups of essential tremor characterized by significant variability of the tremor amplitude and duration. The first subgroup has kinetic tremor prevailing over postural tremor, predominantly asymmetric; the second subgroup is represented by high-amplitude symmetric posture-kinetic tremor; the third group has low-amlitude posture-kinetic tremor. Tremor mostly limits role activity with relative preservation of the ability to perform general physical exercise. Patients with ET are defined by medium and low estimate of physical and mental components of the QoL. The QoL was estimated lowest by the patients of subgroup 2, whereas the health physical component was higher in patients of group 3 which was complemented by a shorter duration of tremor.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>эссенциальный тремор</kwd><kwd>треморография</kwd><kwd>неоднородность тремора</kwd><kwd>качество жизни</kwd><kwd>essential tremor</kwd><kwd>tremorography</kwd><kwd>heterogeneity of tremor</kwd><kwd>quality of life</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Иванова Е.О. Клинико-нейрофизиологический анализ дрожательного гиперкинеза при эссенциальном треморе и болезни Паркинсона: диссертация.. канд. мед. наук. - М. - 2014. - 114 с.</mixed-citation><mixed-citation xml:lang="en">Иванова Е.О. 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