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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">bekhterev</journal-id><journal-title-group><journal-title xml:lang="ru">Обозрение психиатрии и медицинской психологии имени В.М.Бехтерева</journal-title><trans-title-group xml:lang="en"><trans-title>V.M. BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2313-7053</issn><issn pub-type="epub">2713-055X</issn><publisher><publisher-name>V. M. BEKHTEREV  NATIONAL  RESEARCH  MEDICAL  CENTER  FOR  PSYCHIATRY  AND  NEUROLOGY                           OF    THE  RUSSIAN  FEDERATION   MINISTRY  OF  HEALTH</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31363/2313-7053-2024-775</article-id><article-id custom-type="elpub" pub-id-type="custom">bekhterev-918</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>INVESTIGATIONS</subject></subj-group></article-categories><title-group><article-title>Индивидуально-психологические характеристики и особенности совладания с заболеванием у пациентов с первым психотическим эпизодом и постпсихотической депрессией как мишени для психосоциальных интервенций</article-title><trans-title-group xml:lang="en"><trans-title>Individual psychological characteristics and features of coping with the disease in patients with the first psychotic episode and post-psychotic depression as targets for psychosocial interventions</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6835-8613</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Антохин</surname><given-names>Е. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Antokhin</surname><given-names>E. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Антохин Евгений Юрьевич – к. м. н., доцент, заведующий кафедрой клинической психологии и психотерапии</p><p>Оренбург</p></bio><bio xml:lang="en"><p>Evgeny Yu. Antokhin</p><p>Orenburg </p></bio><email xlink:type="simple">antioh73@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5116-836X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Васильева</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Vasilyeva</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Васильева Анна Владимировна - д.м.н., профессор, главный научный сотрудник отделения лечения пограничных психических расстройств и психотерапии, руководитель международного отдела; профессор кафедры психотерапии, медицинской психологии и сексологии</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Anna V. Vasilyeva</p><p>St. Petersburg</p></bio><email xlink:type="simple">annavdoc@yahoo.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7589-0579</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Болдырева</surname><given-names>Т. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Boldyreva</surname><given-names>T. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Болдырева Татьяна Александровна – к. пс.н., доцент кафедры общей психологии и психологии личности</p><p>Оренбург</p></bio><bio xml:lang="en"><p>Tatyana A. Boldyreva</p><p>Orenburg </p></bio><email xlink:type="simple">ttatianna@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1761-1337</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Антохина</surname><given-names>Р. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Antokhina</surname><given-names>R. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Антохина Розалия Ильдаровна - старший преподаватель кафедры клинической психологии и психотерапии</p><p>Оренбург</p></bio><bio xml:lang="en"><p>Rosaliya I. Antokhina</p><p>Orenburg </p></bio><email xlink:type="simple">rozaliana8@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Оренбургский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Orenburg State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Национальный медицинский исследовательский центр психиатрии и неврологии им. В.М. Бехтерева ; Северо-Западный государственный медицинский университет им. И.И. Мечникова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.M. Bekhterev National Research Medical Center for Psychiatry and Neurology; I.I. Mechnikov North-western Medical State University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Оренбургский государственный университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Orenburg State University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>08</day><month>02</month><year>2024</year></pub-date><volume>58</volume><issue>1</issue><fpage>78</fpage><lpage>90</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Антохин Е.Ю., Васильева А.В., Болдырева Т.А., Антохина Р.И., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Антохин Е.Ю., Васильева А.В., Болдырева Т.А., Антохина Р.И.</copyright-holder><copyright-holder xml:lang="en">Antokhin E.Y., Vasilyeva A.V., Boldyreva T.A., Antokhina R.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.bekhterevreview.com/jour/article/view/918">https://www.bekhterevreview.com/jour/article/view/918</self-uri><abstract><sec><title>Цель исследования</title><p>Цель исследования: определить индивидуально-психологические характеристики и особенности совладания с заболеванием у пациентов с первым психотическим эпизодом и постпсихотической депрессией для выделения мишеней последующих психосоциальных интервенций. Обследовано 1112 больных, перенесших первый психотический эпизод, из которых после введения критериев включения/исключения сформировано в конечном дизайне две группы: 243 пациента с постпсихотической депрессией и 119 пациентов без депрессии в частичной ремиссии. Использованы клинико-психопатологический метод с объективизацией шкалами PANSS, CDSS, клинико-психологический метод с диагностикой копинга, механизмов психологической защиты, перфекционизма и самостигматизации стандартизированными опросниками, проведен регрессионный анализ методом множественной линейной регрессии с пошаговым включением. Из числовых характеристик выборок определены среднее арифметическое с вычислением стандартной ошибки среднего, стандартного отклонения. Статистически значимыми приняты результаты на уровне значимости p&lt;0,05.</p></sec><sec><title>Выводы</title><p>Выводы: проведенное исследование установило значимое влияние на клинические проявления постпсихотической депрессии у больных, перенесших ППЭ шизофрении, всех изученных индивидуально-психологических характеристик с наибольшей активностью копинга, что указывает на несомненное участие реактивных механизмов в развитии данного вида патологии. Это подтверждает значимость в лечение изученной когорты пациентов, не только дифференцированной психофармакотерапии, но и активного психотерапевтического сопровождения с проработкой выделенных «мишеней» копинга, индивидуально-психологических характеристик.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Purpose of the study</title><p>Purpose of the study: to determine the individual psychological characteristics and features of coping with the disease in patients with the first psychotic episode and post-psychotic depression in order to identify targets for subsequent psychosocial interventions. We examined 1112 patients who underwent the first psychotic episode, of which, after the introduction of inclusion/exclusion criteria, two groups were formed in the final design: 243 patients with postpsychotic depression and 119 patients without depression in partial remission. Clinical and psychopathological method with objectification by PANSS, CDSS scales, clinical and psychological method with diagnostics of coping, psychological defense mechanisms, perfectionism and self-stigmatization by standardized questionnaires were used, regression analysis was carried out using the method of multiple linear regression with stepwise inclusion. From the numerical characteristics of the samples, the arithmetic mean was determined with the calculation of the standard error of the mean, standard deviation. Statistically significant results were accepted at the p&lt;0.05 significance level.</p></sec><sec><title>Conclusions</title><p>Conclusions: the study found a significant effect on the clinical manifestations of postpsychotic depression in patients who underwent PES of schizophrenia, all studied individual psychological characteristics with the highest coping activity, which indicates the undoubted involvement of reactive mechanisms in the development of this type of pathology. This confirms the importance in the treatment of the studied cohort of patients, not only of differentiated psychopharmacotherapy, but also of active psychotherapeutic support with the study of selected “targets” of coping, individual psychological characteristics.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>постпсихотическая депрессия</kwd><kwd>первый эпизод шизофрении</kwd><kwd>копинг</kwd><kwd>самостигматизация</kwd><kwd>перфекционизм</kwd><kwd>психологическая защита</kwd></kwd-group><kwd-group xml:lang="en"><kwd>post-psychotic depression</kwd><kwd>first episode of schizophrenia</kwd><kwd>coping</kwd><kwd>self-stigmatization</kwd><kwd>perfectionism</kwd><kwd>psychological defense</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Антохин Е.Ю., Будза В.Г., Крюкова Е.М., Палаева Р.И. 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