Psychiatric conditions with a known pathogenesis: anti-NMDAr encephalitis in the field of pediatric and adolescent psychiatry
Aleksandr V. Abramov,
Evgenii V. Makushkin,
Yulia A. Chaika,
Alexander V. Goryunov,
Galina D. Guseva,
Margarita A. Menshikova,
Marina E. Farnosova https://doi.org/10.31363/2313-7053-2025-3-1056
Abstract
The relevance of studying mental disorders in anti-NMDA encephalitis is due to a number of aspects: psychopathological manifestations in anti-NMDA encephalitis are polymorphic and manifest in the form of an acute psychotic disorder resistant to neuroleptic therapy is not uncommon; cases with periodic course are described; patients of childhood, adolescence and young age are more predisposed to the development of the disease, the quality of prognosis is associated with early the beginning of pathogenetic immunosuppressive therapy. Objective: to describe psychopathological manifestations in autoimmune encephalitis in a group of adolescent patients. Material and methods: the clinical and dynamic features of the course of autoimmune anti-NMDA receptor encephalitis in the acute and recovery period in four adolescent patients were studied. Conclusion: the study revealed specific disorders characteristic of organic mental disorders in the acute period of the disease and symptom complexes that might determine the severity of the disease – reversible regression of the psyche, cognitive impairment, motor coordination disorders.
About the Authors
Aleksandr V. Abramov
Scientific and Practical Center for Mental Health of Children and Adolescents named after G.E. Sukhareva; Mental Health Research Centre
Russian Federation
Russian Federation
Moscow
Evgenii V. Makushkin
MEDSI Mental Health Center
Russian Federation
Russian Federation
Moscow
Yulia A. Chaika
Mental Health Research Centre
Russian Federation
Russian Federation
Moscow
Alexander V. Goryunov
Mental Health Research Centre
Russian Federation
Russian Federation
Moscow
Galina D. Guseva
Infectious Clinical Hospital No. 1
Russian Federation
Russian Federation
Moscow
Margarita A. Menshikova
Children Hospital of Z.A. Bashlyaeva
Russian Federation
Russian Federation
Moscow
Marina E. Farnosova
Children Hospital of Z.A. Bashlyaeva
Russian Federation
Russian Federation
Moscow
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For citations:
Abramov A.V., Makushkin E.V., Chaika Yu.A., Goryunov A.V., Guseva G.D., Menshikova M.A., Farnosova M.E. Psychiatric conditions with a known pathogenesis: anti-NMDAr encephalitis in the field of pediatric and adolescent psychiatry. V.M. BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY. (In Russ.) https://doi.org/10.31363/2313-7053-2025-3-1056
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