The relationship between anxiety disorders and alcohol use: predictors and predictive modeling
https://doi.org/10.31363/2313-7053-2025-3-1092
Abstract
Anxiety disorders (AD) and risky alcohol use are often interrelated, creating a vicious cycle that reduces treatment efficacy and patients' quality of life. A study involving 120 AD patients identified key predictors of risky alcohol consumption. Patients with generalized anxiety disorder were found to have a 2.3 times higher risk of alcohol abuse compared to those with episodic anxiety. Key risk factors included high levels of neuroticism, emotional discomfort, phobic reactions, and a lack of adaptive coping strategies. Using CHAID analysis and logistic regression, researchers developed a predictive model with high accuracy (AuROC=0.937), which takes into account both clinical and individual psychological characteristics. The results highlight the importance of considering the type of anxiety and associated psychological traits when designing prevention programs. For patients with generalized anxiety, the focus should be on reducing emotional discomfort and phobic reactions, while for those with episodic anxiety, developing emotional support-seeking skills and addressing neuroticism are crucial. The findings align with current understanding of the relationship between anxiety disorders and alcohol use, offering practical recommendations for clinical practice. The study contributes to a deeper understanding of the mechanisms underlying the transition from moderate to risky alcohol use in patients with anxiety disorders and suggests directions for further research, including the role of coping strategies and the development of comprehensive prevention models.
About the Authors
Dmitriy S. Radionov
V.M. Bekhterev National Research Medical Center for Psychiatry and Neurology
Russian Federation
Russian Federation
Saint Petersburg
Tatiana A. Karavaeva
V.M. Bekhterev National Research Medical Center for Psychiatry and Neurology; Saint-Petersburg State University; Saint-Petersburg State Pediatric Medical University; N.N. Petrov National Medical Research Centre of Oncology
Russian Federation
Russian Federation
Saint Petersburg
References
1. Belinskaya EP, Veсherin AV. Adaptation of “Proactive coping inventory”. Social'naya psihologiya i obshchestvo. 2018;9(3):137—145. (In Russ.). https://doi.org/10.17759/cpse.2018070312
2. Belinskaya EP, Veсherin AV, Agadullina ER. Proactive Coping Inventory: Adaptation to a Non-Clinical Sample and the Predictive Capability. Klinicheskaya i special'naya psihologiya. 2018;7(3):192–211. (In Russ.). https://doi.org/10.17759/psycljn.2018070312
3. Vasileva A.V. i dr. Generalizovannoe trevozhnoe rasstroistvo: Vzroslye. Moskva: Ministerstvo zdravookhraneniya Rossii, 2024. (In Russ.).
4. Vasileva A.V. i dr. Panicheskoe rasstroistvo: Vzroslye. Moskva: Ministerstvo zdravookhraneniya Rossii, 2024. (In Russ.).
5. Vasileva A.V. i dr. Trevozhno-fobicheskie rasstroistva: Vzroslye. Moskva: Ministerstvo zdravookhraneniya Rossii, 2024. (In Russ.).
6. Vasserman L.I., Shchelkova O.Yu. Psikhologicheskaya diagnostika rasstroistv emotsional'noi sfery i lichnosti: kollektivnaya monografiya. SPb.: SPbGU, 2014. (In Russ.).
7. Iovlev B.V., Karpova E.B., Vuks A.Ya., Vasserman L.I. Shkala dlya psikhologicheskoi ekspress-diagnostiki urovnya nevrotizatsii. SPb.: NIPNI im. Bekhtereva, 1999. (In Russ.).
8. Klimanova SG, Berezina AA, Trusova AV, Podoliak DV, Rybakova KV, Krupitsky EM. The relationship between the clinical characteristics of patients with alcohol use disorder and drinking motives. Obozrenie psihiatrii i medicinskoj psihologii imeni V.M. Bekhtereva. 2022;56(4):63-76. (In Russ.). https://doi.org/10.31363/2313-7053-2022-4-63-76
9. Radionov DS, Karavaeva ТА. Clinical characteristics of patients with anxiety disorders who have a certain level of alcohol consumption. Voprosy narkologii. 2024;36(3):56-71. (In Russ.).
10. Radionov DS, Karavaeva ТА, Vasileva АV, Rybakova KV, Krupitsky EM, Prusova TI. Peculiarities of alcohol abuse by individuals with neurotic spectrum anxiety disorders. Clinical aspects and issues of psychotherapy. Voprosy narkologii. 2023;35(3):27–50 . (In Russ.).
11. Radionov DS, Tverdokhlebova AM, Karavaeva ТА. Analysis of individual psychological characteristics of patients with anxiety disorders who have a certain level of alcohol consumption. Voprosy narkologii. 2024;36(6):29-54. (In Russ.).
12. Shalnova SA, Evstifeeva SE, Deev AD et al. The prevalence of anxiety and depression in different regions of the Russian Federation and its association with sociodemographic factors (according to the data of the ESSE-RF study). Terapevticheskij arhiv. 2014;86(12):53-60. (In Russ.). https://doi.org/10.17116/terarkh2014861253-60
13. Bimstein JG, O'Bryan EM, Jean A, McLeish AC. Intolerance of Uncertainty, Negative Reinforcement Alcohol Use Motives, and Hazardous Drinking in College Students with Clinically Elevated Worry. Subst Use Misuse. 2023;58(10):1254-1261. https://doi.org/10.1080/10826084.2023.2215318
14. Boschloo L, Vogelzangs N, van den Brink W, et al. Alcohol use disorders and the course of depressive and anxiety disorders. Br J Psychiatry. 2012;200(6):476-484. https://doi.org/10.1192/bjp.bp.111.097550
15. Cook S, Kudryavtsev A, Bobrova N et al. Prevalence of symptoms, ever having received a diagnosis and treatment of depression and anxiety, and associations with health service use amongst the general population in two Russian cities. BMC Psychiatry. 2020;20. https://doi.org/10.1186/s12888-020-02938-w.
16. Gorkin AN, Anderson KG. Intolerance of Uncertainty, Drinking Motives, and Alcohol Consumption in a Community Sample of Emerging Adults. Cogn Ther Res. 2024;48:1202–1213. https://doi.org/10.1007/s10608-024-10512-x
17. Liu D, Luo M, Huang Y, Tan Y, Cheng F, Wu Y. Time trends in anxiety disorders incidence across the BRICS: an age-period-cohort analysis for the GBD 2021. Front Public Health. 2024;12:1467385. https://doi.org/10.3389/fpubh.2024.1467385
18. Puddephatt JA, Irizar P, Jones A, Gage SH, Goodwin L. Associations of common mental disorder with alcohol use in the adult general population: a systematic review and meta-analysis. Addiction. 2022;117(6):1543-1572. https://doi.org/10.1111/add.15735
19. Rostam-Abadi Y, Gholami J, Shadloo B, et al. Alcohol use, alcohol use disorder and heavy episodic drinking in the Eastern Mediterranean region: A systematic review. Addiction. 2024;119(6):984-997. https://doi.org/10.1111/add.16444
20. Shield K, Manthey J, Rylett M, et al. National, regional, and global burdens of disease from 2000 to 2016 attributable to alcohol use: a comparative risk assessment study. Lancet Public Health. 2020;5(1):e51-e61. https://doi.org/10.1016/S2468-2667(19)30231-2
21. Taylor AW, Bewick BM, Makanjuola AB, Qian L, Kirzhanova VV, Alterwain P. Context and culture associated with alcohol use amongst youth in major urban cities: A cross-country population based survey. PLoS One. 2017;12(11):e0187812. https://doi.org/10.1371/journal.pone.0187812
22. Yang X, Fang Y, Chen H, et al. Global, regional and national burden of anxiety disorders from 1990 to 2019: results from the Global Burden of Disease Study 2019. Epidemiol Psychiatr Sci. 2021;30:e36. https://doi.org/10.1017/S2045796021000275
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For citations:
Radionov D.S., Karavaeva T.A. The relationship between anxiety disorders and alcohol use: predictors and predictive modeling. V.M. BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY. (In Russ.) https://doi.org/10.31363/2313-7053-2025-3-1092
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