Когнитивные нарушения при трансплантации костного мозга (обзор литературы)

В статье представлен обзор литературы, посвященной когнитивным нарушениям, выявляемым у пациентов с заболеваниями системы крови до и после трансплантации костного мозга. Рассматриваются факторы риска развития когнитивных нарушений у таких больных - полихимиотерапия, миелоаблативная и иммуносупрессивная терапия, тревожные и депрессивные расстройства, посттравматическое-стрессовое расстройство, астенический синдром. Отмечается, что этиологическая многофакторность данных расстройств диктует необходимость одновременно оценивать влияние психопатологическое состояния, нейропсихологического и неврологического статуса больных, протоколов лечения, показателей ЭЭГ, МРТ и их динамику.

трансплантация костного мозга, когнитивные расстройства, мягкая деменция, психические расстройства, депрессия, тревога, ПТСР, bone marrow transplantation, cognitive disorders, mild dementia, mental disorders, depression, anxiety, PTSD

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