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Use of third-generation antipsychotics in combination with clozapine in the treatment of resistant schizophrenia

https://doi.org/10.31363/2313-7053-2025-2-1147

Abstract

The aim of the study was to analyze the pathogenesis and treatment strategies of treatment-resistant schizophrenia by searching, selecting and reviewing publications covering this topic. 42 articles were analyzed during the work, which contributed to the conclusion about the effectiveness and good tolerability of third-generation antipsychotics in patients with resistant schizophrenia taking clozapine, and also to formulate the conclusion that third-generation antipsychotics can be effective in such cases.

About the Authors

A. R. Asadullin
Bashkir State Medical University
Russian Federation

Azat R. Asadullin 

Uf



P. O. Bomov
North-Western State Medical University named after I.I. Mechnicov
Russian Federation

Pavel O. Bomov 

St. Petersburg



Yu. A. Bogod
North-Western State Medical University named after I.I. Mechnicov
Russian Federation

Yulia A. Bogod

St. Petersburg



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Review

For citations:


Asadullin A.R., Bomov P.O., Bogod Yu.A. Use of third-generation antipsychotics in combination with clozapine in the treatment of resistant schizophrenia. V.M. BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY. 2025;59(2):114-121. (In Russ.) https://doi.org/10.31363/2313-7053-2025-2-1147

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ISSN 2313-7053 (Print)
ISSN 2713-055X (Online)