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The Burden of Tardive Dyskinesia in Patients with Mental Disorders

https://doi.org/10.31363/2313-7053-2025-4-1261

Abstract

Tardive tardive dyskinesia (TD) is a serious, often disabling movement disorder caused by dopamine receptor blocking drugs, including antipsychotics. TD is quite common, but controlling risk factors can, in theory, reduce the likelihood of iatrogenic development. TD has a colossal negative impact on all areas of a patient's life, including physical and psychological well-being, social satisfaction, and the course of the underlying mental illness. Currently, there is no standard treatment approach. However, specialists have treatment options that can significantly alleviate the condition. One such drug is amantadine sulfate (PК-Merz), which has demonstrated sufficient efficacy and safety in this patient population.

About the Authors

D. V. Zakharov
V.M. Bekhterev National Medical Research Centre for Psychiatry and Neurology
Russian Federation

Denis V. Zakharov

St. Petersburg



N. G. Neznanov
V.M. Bekhterev National Medical Research Centre for Psychiatry and Neurology
Russian Federation

Nikolay G. Neznanov

St. Petersburg



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For citations:


Zakharov D.V., Neznanov N.G. The Burden of Tardive Dyskinesia in Patients with Mental Disorders. V.M. BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY. 2025;59(4):18-24. (In Russ.) https://doi.org/10.31363/2313-7053-2025-4-1261

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