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Genes of dopamine receptors and transporter in patients with schizophrenia: associations with the clinical characteristics of the disorder

https://doi.org/10.31363/2313-7053-2019-4-1-93-94

Abstract

Genotyping of 28 polymorphisms of 5 dopamine receptor genes and 12 polymorphisms of dopamine transporter gene was performed in 475 schizophrenia patients and 135 healthy individuals. Associations of several polymorphisms of the DRD2, DRD3 and SLC6A3 genes were identified with leading symptoms and late debut of schizophrenia.

About the Authors

A. S. Boiko
Mental Health Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciences
Russian Federation


I. V. Pozhidaev
Mental Health Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciences
Russian Federation


O. Z. Paderina
Mental Health Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciences
Russian Federation


A. V. Semke
Mental Health Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciences
Russian Federation


References

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Review

For citations:


Boiko A.S., Pozhidaev I.V., Paderina O.Z., Semke A.V. Genes of dopamine receptors and transporter in patients with schizophrenia: associations with the clinical characteristics of the disorder. V.M. BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY. 2019;(4-1):93-94. (In Russ.) https://doi.org/10.31363/2313-7053-2019-4-1-93-94

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ISSN 2313-7053 (Print)
ISSN 2713-055X (Online)