Effects of the COMT Val158Met polymorphism on N100 component of auditory evoked potential and oddball task performance in healthy subjects and schizophrenia patients
https://doi.org/10.31363/2313-7053-2019-4-1-109-111
Abstract
The study was conducted with the participation of 47 healthy subjects and 48 schizophrenia patients. The different effects of Val158Met polymorphism have been found in the control and patients groups. The increased N100 amplitude and minimal number of the error responses in oddball task were revealed in healthy subjects with Val/Val genotype. In patients group Val/Val genotype was related to the decreased N100 amplitude and worse performance of oddball task.
About the Authors
A. A. Fedotova
Lomonosov Moscow State University
Russian Federation
Russian Federation
A. V. Kirenskaya
Federal State Budgetary Institution “V. Serbsky National Medical Research Centre for Psychiatry and Narcology” of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
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Review
For citations:
Fedotova A.A., Kirenskaya A.V. Effects of the COMT Val158Met polymorphism on N100 component of auditory evoked potential and oddball task performance in healthy subjects and schizophrenia patients. V.M. BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY. 2019;(4-1):109-111. (In Russ.) https://doi.org/10.31363/2313-7053-2019-4-1-109-111
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