Non-Epileptic Paroxysmal Events in Infants: stucture, manifestation and risk factors
https://doi.org/10.31363/2313-7053-2020-2-80-86
Abstract
During 3 years we observed in specialized neurological department of St. Olga Children’s City Hospital 708 babies aged up to 42 months with different paroxysmal disorders. Non-epileptic paroxysmal events (NEPE) were diagnosed in 98 cases. These disorders were qualified (according to ILAE criteria) as differentiated and undifferentiated NEPE. In most cases neurophysiological assessment data, neurovisualization data, and neurological status of infants with NEPE and babies from comparison group varied marginally. It was shown that NEPE development correlated with perinatal factors, and with infants’ developmental diseases (functional gastrointestinal disorders, iron deficiency states, chronic or persistent infections). The obtained data was interpreted according to the developmental neurology principles (optimality concept, in particular).
About the Authors
V. V. Privorotskaya
St.Petersburg State Pediatric Medical University of the Ministry of Health of the Russian Federation;
St.Olga Children Hospital
Russian Federation
Russian Federation
A. B. Palchik
St.Petersburg State Pediatric Medical University of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
A. E. Ponyatishin
St.Petersburg State Pediatric Medical University of the Ministry of Health of the Russian Federation;
St.Olga Children Hospital
Russian Federation
Russian Federation
G. A. Mashevskiy
State Electrotechnical University
Russian Federation
Russian Federation
References
1. Aivazyan S.O. Neepilepticheskie paroxysmal’nye sostoyaniya, imitiruyuschie epilepsiyu u detey. Epilepsiya i paroxysmal’nye sostoyaniya. 2016;8:23-33 (in Russ.).
2. Guzeva V.I. Epilepsiya i neepilepticheskie paroxysmal’nye sostoyaniya u detey. M.: Meditsinskoye informatsionnoe agenstvo. 2007; 568 (in Russ.).
3. Mukhin K.Yu. Epilepticheskie syndromy. Diagnostika i terapiya. Spravochnoye rukovodstvo dlya vrachey. Pod red. K.Yu. Mukhina, A.S. Petrukhina, M.B. Mironova. M.: Systemnye resheniya. 2008;223 (in Russ.).
4. Neepilepticheskie paroxysmal’nye rasstroystva u detey. Uchebno-metodicheskoye posobie. Pod red. D.D. Korostovtseva, V.I. Guzevoy, M.Yu. Fominoyi dr. SPb. :SPbGPMA. 2006;41 (in Russ.).
5. Pal’chik AВ. Osnovnye principy nevrologii razvitiya. Pediatr 2011;2 (3):90-97. (in Russ.).
6. Pal’chikA.В., Ponyatishin A.E. Neepilepticheskie paroxysmy u grudnykh detey. М.:MEDpress-inform. 2015;136. (in Russ.).
7. Khanin Yu.L. Kratkoe rukovodstvo k primeneniyu shkaly reaktivnoy I lichnostnoy trevozhnosti C.D. Spielbergera. L.: LNIIFK. 1976;18. (in Russ.)
8. Carabotti M, Scirocco A, Maselli MA, Severi C. The gut-brain axis: interactions between enteric microbiota, central and enteric nervous systems. Annals of Gastroenterology. 2015;28(2):203—9.
9. Drossman DA, Hasler WL. Rome IV—Functional GI Disorders: Disorders of Gut-Brain Interaction. Gastroenterology. 2016; 150(6): 1257–61.
10. Fejerman N. Nonepileptic disorders imitating generalized idiopathic epilepsies. Epilepsia. 2005; 46 (9):80–3.
11. Hamed SA, Gad EF, Sherif TK. Iron deficiency and cyanotic breath-holding spells: The effectiveness of iron therapy. Pediatric Hematology and Oncology. 2018;35(3):186–95.
12. Kainer F, Prechtl H, Engele H, Einspieler C. Assessment of the quality of general movements in fetuses and infants of women with type-I diabetes mellitus. Early Human Development. 1997;50(1):13–25.
13. Kim SH, Kim H, Lim BC et al. Paroxysmal nonepileptic events in pediatric patients confirmed by long-term video-EEG-monitoring — single tertiary center of 143 patients. Epilepsy and Behavior. 2012;24(3):336–40.
14. Kotagal P, Costa M, Wyllie E, Wolgamuth B. Paroxysmal nonepileptic events in children and adolescents. Pediatrics. 2002;110(4):46.
15. Luders H, Noachtar S. Atlas and Classification of Electroencephalography.—Philadelphia: Saunders. 2000; 203.
16. Maqsood R, Stone T. The gut-brain axis, BDNF, NMDA and CNS disorders. Neurochemical Research. 2016;41(11):2819–35.
17. Mattie-Luksic M, Javornisky G, Di Mario FJ. Assessment of stress in mothers of children with severe breath-holding spells. Pediatrics. 2000; 106:1–5.
18. Prechtl HFR. The optimality concept. Early Human Development.1980;4(3):201–5.
19. Spielberger CD, Gorsuch RL, Lushene PR et al. Manual for the State-Trait Anxiety Inventory (Form Y). Palo Alto, CA: Consulting Psychologists Press. 1983; 42.
20. Uldall P, Alving J, Hansen LK et al. The misdiagnosis of epilepsy in children admitted to a tertiary epilepsy center with paroxysmal events. Archives of Disease in Childhood. 2006;91(3):219–21.
21. Visser AM, Jaddoe WV, Arends LR et al. Paroxysmal disorders in infancy and their risk factors in a population-based cohort: the Generation R Study. Developmental Medicine and Child Neurology. 2010;52 (11):1014–20.
22. Wakefield AJ. The Gut–Brain Axis in Childhood Developmental Disorders. Journal of Pediatric Gastroenterology and Nutrition. 2002;34:14–7.
23. Wolke D, Bilgin A, Samara M. Systematic Review and Meta-Analysis: Fussing and Crying Durations and Prevalence of Colic in Infants. The Journal of Pediatrics. 2017;185:55–61.
24. Официальный сайт Международной Антиэпилептической Лиги [Электронный ресурс]. Режим доступа: https://www.ilae.org.
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For citations:
Privorotskaya V.V., Palchik A.B., Ponyatishin A.E., Mashevskiy G.A. Non-Epileptic Paroxysmal Events in Infants: stucture, manifestation and risk factors. V.M. BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY. 2020;(2):80-86. (In Russ.) https://doi.org/10.31363/2313-7053-2020-2-80-86
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